iphone 7 plus case 投稿者：Fred 投稿日：2018/06/19(Tue) 07:25 No.9331844 |
Furthermore, when the control group is accurate (or even when the standard of care's positive response is overestimated), single arm studies have been scientifically demonstrated to be highly accurate (sometimes more so than randomized trials).Figure by Valeria Sambucini Journal of Biopharmaceutical StatisticsTo clarify this statement, these two graphs demonstrate the probability of a properly interpreted result based on various levels of success and statistical probabilities. In short, you want a high probability (higher on the y axis) on the left, as you approach the statistically significant level of plarge centers for the analysis which treat significant levels of patients as desirable. The use of such large centers decreases patient drift and variability and tends to support the use of single arm studies by improving on the statistics of the patient pool and decreasing random variability.
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